topical tranexamic acid as a promising treatment for melasma
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Topical tranexamic acid as a promising treatment for melasma
BACKGROUND In recent times, tranexamic acid (TA) is claimed to have whitening effects especially for ultraviolet-induced hyperpigmentation including melasma. The aim of our study was to evaluate the efficacy and safety of topical solution of TA and compare it with combined solution of hydroquinone and dexamethasone as the gold standard treatment of melasma in Iranian women. MATERIALS AND METH...
متن کاملOral tranexamic acid for the treatment of melasma.
BACKGROUND Melasma poses a great challenge as its treatment is unsatisfactory and recurrence is high. Treatment of melasma using tranexamic acid (oral, topical or intralesional) is a novel concept. OBJECTIVE To compare the efficacy of oral tranexamic acid with routine topical therapies for the treatment of melasma. METHODS It is a prospective, interventional, randomized controlled trial con...
متن کاملTherapeutic Effects of Topical Tranexamic Acid in Comparison with Hydroquinone in Treatment of Women with Melasma
INTRODUCTION Few studies have focused on therapeutic as well as side effects of tranexamic acid (TXA) as a topical drug compared to other topical drugs in treating melasma. The present study aimed to assess and compare the beneficial therapeutic effects and also side effects of local TXA in comparison with hydroquinone in treating women with melasma. METHODS This randomized double-blinded cli...
متن کاملTranexamic Acid in Melasma: A Review
Melasma is a localized, chronic acquired hypermelanosis of the skin. Despite several treatments available, melasma can often be refractory to treatment. Also recurrences are common. Tranexamic acid is a new addition in treatment of melasma and is effective in dosage of 250 mg BD for atleast 4 to 8 weeks. Tranexamic acid acts mainly via the plasminogen activator-plasmin system to prevent UV radi...
متن کاملTranexamic acid: an important adjuvant in the treatment of melasma.
This article reviews an old drug tranexamic acid to its new use in the treatment of melasma. Its mechanism of preventing the activation of melanocyte from UV light, hormone and injured kerationcyte through the inhibition of the plasminogen activator system will be explored. The detail usage for such indication and its safety profile will also be thoroughly evaluated.
متن کاملEfficacy of functional microarray of microneedles combined with topical tranexamic acid for melasma
To evaluate the efficacy of a functional microarray of microneedles (MNs) plus topical tranexamic acid (TA) for melasma in middle-aged women in China.Thirty female subjects with melasma were enrolled in this study. The left or right side of the face was chosen randomly to be pretreated with a functional microarray of MNs, followed by topical 0.5% TA solution once per week for 12 weeks. The othe...
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عنوان ژورنال:
journal of research in medical sciencesجلد ۱۹، شماره ۸، صفحات ۰-۰
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